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Synthesis and Antibacterial Activity of Polymerizable Acryloyloxyalkyltriethyl Ammonium Salts
Author(s) -
Mancuso Raffaella,
Amuso Roberta,
Armentano Biagio,
Grasso Giuseppe,
Rago Vittoria,
Cappello Anna Rita,
Galiano Francesco,
Figoli Alberto,
De Luca Giorgio,
Hoinkis Jan,
Gabriele Bartolo
Publication year - 2017
Publication title -
chempluschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.801
H-Index - 61
ISSN - 2192-6506
DOI - 10.1002/cplu.201700329
Subject(s) - ammonium , antibacterial activity , chemistry , combinatorial chemistry , organic chemistry , bacteria , genetics , biology
Abstract Invited for this month's cover are the collaborating groups at the University of Calabria (Unical, Italy)—Department of Chemistry and Chemical Technologies (CTC) and Department of Pharmacy and Health and Nutritional Sciences (PHNS), at the National Research Council (CNR, Italy), Institute on Membrane Technology (ITM), and at the Karlsruhe University of Applied Sciences (HSKA, Germany), Institute of Applied Research (IAR), which cooperated in the framework of the European Union's Horizon 2020 project “VicInAqua”. The front cover shows the structure of an acryloxyalkyltrithylammonium (AATEA) cation, characterized by a polymerizable end, a long‐chain alkyl linker, and a quaternary ammonium moiety. The bromide salts (AATEABs) have been synthesized by a two‐step procedure carried out entirely under air without any need for chromatographic purifications. Some AATEABs have shown significant antimicrobial activity and represent useful precursors for the preparation of polymeric films with antimicrobial properties. Read the full text of the article at 10.1002/cplu.201700194.