Premium
Cellular Internalization and Biocompatibility of Periodic Mesoporous Organosilica Nanoparticles with Tunable Morphologies: From Nanospheres to Nanowires
Author(s) -
Fatieiev Yevhen,
Croissant Jonas G.,
Alamoudi Kholod,
Khashab Niveen M.
Publication year - 2017
Publication title -
chempluschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.801
H-Index - 61
ISSN - 2192-6506
DOI - 10.1002/cplu.201600560
Subject(s) - biocompatibility , nanomaterials , materials science , nanotechnology , nanoparticle , nanowire , mesoporous organosilica , template , mesoporous material , internalization , aqueous solution , mesoporous silica , chemical engineering , chemistry , organic chemistry , catalysis , biochemistry , engineering , cell , metallurgy
This work describes the sol–gel syntheses of para ‐substituted phenylene‐bridged periodic mesoporous organosilica (PMO) nanoparticles (NPs) with tunable morphologies ranging from nanowires to nanospheres. The findings show the key role of the addition of organic co‐solvents in the aqueous templates on the final morphologies of PMO NPs. Other factors such as the temperature, the stirring speed, and the amount of organic solvents also influence the shape of PMO NPs. The tuning of the shape of the PMO nanomaterials made it possible to study the influence of the particle morphology on the cellular internalization and biocompatibility.