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A Water‐Soluble Copper(II) Complex for the Selective Fluorescence Detection of Nitric Oxide/Nitroxyl and Imaging in Living Cells
Author(s) -
Sun Xiaolong,
Kim Gyoungmi,
Xu Yufang,
Yoon Juyoung,
James Tony D.
Publication year - 2016
Publication title -
chempluschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.801
H-Index - 61
ISSN - 2192-6506
DOI - 10.1002/cplu.201500436
Subject(s) - chemistry , nitroxyl , nitric oxide , fluorescence , analyte , copper , reactive oxygen species , inorganic chemistry , photochemistry , organic chemistry , chromatography , biochemistry , physics , quantum mechanics
A novel water‐soluble copper(II) naphthalimide complex fluorescent probe was devised and displayed significant fluorescence turn‐on response for nitric oxide and nitroxyl over other biologically relevant reactive oxygen species under physiological conditions. The dual‐analyte recognition of this simple and sensitive probe was successfully applied for the imaging of exogenous and endogenous NO and HNO in living cells.