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Direct Oxidative Amidation between N,N ‐dimethylanilines and Anhydrides Using Metal‐Organic Framework [Cu 2 (EDB) 2 (BPY)] as an Efficient Heterogeneous Catalyst
Author(s) -
Dang Giao H.,
Nguyen Thanh D.,
Le Dung T.,
Truong Thanh,
Phan Nam T. S.
Publication year - 2014
Publication title -
chempluschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.801
H-Index - 61
ISSN - 2192-6506
DOI - 10.1002/cplu.201402090
Subject(s) - catalysis , dabco , chemistry , pyridine , selectivity , metal organic framework , heterogeneous catalysis , organic base , homogeneous catalysis , homogeneous , medicinal chemistry , inorganic chemistry , polymer chemistry , organic chemistry , physics , adsorption , thermodynamics
A crystalline porous metal‐organic framework [Cu 2 (EDB) 2 (BPY)] was synthesized and used as a heterogeneous catalyst for the direct oxidative amidation between N,N ‐dimethylanilines and anhydrides to form tertiary amides as the principal products. The [Cu 2 (EDB) 2 (BPY)] exhibited similar activity as compared to that of [Cu 2 (BDC) 2 (BPY)], [Cu 2 (BDC) 2 (DABCO)], MOF‐143, and other common homogeneous salt catalysts. The optimal reaction conditions employed were [Cu 2 (EDB) 2 (BPY)] (10 % mol), TBHP (2 equiv), pyridine (1 equiv) in CH 3 CN at 80 °C over 2 h. The Cu 2 (EDB) 2 (BPY) could be separated from the reaction mixture by filtration, and could be recovered and reused several times without a significant degradation in catalytic activity and selectivity. Furthermore, generality of the optimal conditions was confirmed by employing various N,N‐ dimethylaniline and anhydride derivatives.