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A Probe for the Selective and Parts‐per‐Billion‐Level Detection of Copper(II) and Mercury(II) using a Micellar Medium and Its Utility in Cell Imaging
Author(s) -
Kumari Namita,
Jha Satadru,
Misra Santosh K.,
Bhattacharya Santanu
Publication year - 2014
Publication title -
chempluschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.801
H-Index - 61
ISSN - 2192-6506
DOI - 10.1002/cplu.201402016
Subject(s) - naked eye , moiety , chemistry , metal ions in aqueous solution , copper , fluorescence , mercury (programming language) , pyrene , amine gas treating , ion , metal , photochemistry , inorganic chemistry , analytical chemistry (journal) , detection limit , organic chemistry , chromatography , optics , physics , computer science , programming language
A novel colorimetric probe 1 based on the picolyl moiety has been designed and synthesized. Probe 1 is composed of a pyrene and a bispicolyl amine (BPA) unit, in which the BPA moiety acts as a binding unit and the binding phenomenon is sensed from the changes in the signaling subunit. The probe detects Cu 2+ specifically in water and both Cu 2+ and Hg 2+ efficiently in neutral Brij‐58 micellar media. The probe shows a color change visible to the naked eye upon addition of metal ions. Notably, in a micellar medium, probe 1 can detect both the Cu 2+ and Hg 2+ ions even at parts‐per‐billion levels. Furthermore, the probe shows ratiometric detection of both the metal ions making the sensing quantitative. The two metal ions could be discriminated both visibly under a UV lamp and with the use of fluorescence spectroscopy. The probe could be also used in biological cell lines for the detection of both Hg 2+ and Cu 2+ ions.