Premium
Quantification of 3‐Monochloropropane‐1,2‐diol Esters in Edible Oils by Large‐Volume Injection Coupled to Comprehensive Gas Chromatography–Time‐of‐Flight Mass Spectrometry
Author(s) -
de Koning Sjaak
Publication year - 2014
Publication title -
chempluschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.801
H-Index - 61
ISSN - 2192-6506
DOI - 10.1002/cplu.201300351
Subject(s) - derivatization , chemistry , chromatography , detection limit , mass spectrometry , gas chromatography , gas chromatography–mass spectrometry , repeatability , extraction (chemistry) , diol , phenylboronic acid , time of flight mass spectrometry , volume (thermodynamics) , organic chemistry , ion , ionization , catalysis , physics , quantum mechanics
3‐Monochloropropane‐1,2‐diol (3‐MCPD) esters are a group of process contaminants formed during the refining of edible oils and fats. A method for the determination of 3‐MCPD esters in such oils and fats based on large‐volume injection–comprehensive gas chromatography–time‐of‐flight mass spectrometry (LVI–GC×GC–ToF MS) is presented. The simplified method for sample preparation consists of alkaline hydrolysis followed by extraction of 3‐MCPD from the lipid matrix and derivatization using phenylboronic acid. The limit of detection was 0.8 μg kg −1 , reported as free 3‐MCPD. The repeatability was better than 2.7 % relative standard deviation for levels around 0.5 μg g −1 3‐MCPD. The GC×GC–ToF MS system was shown to be stable over 100 analyses.