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Arginine Wettability and Impedance Dual‐Signal Response by Aldehyde Calix[4]arene Self‐Assembled Monolayers
Author(s) -
Yang Lanlan,
Luo Li,
Zhang Guifen,
Miao Fajun,
Zhang Xiaoyan,
Tian Demei,
Li Haibing
Publication year - 2013
Publication title -
chempluschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.801
H-Index - 61
ISSN - 2192-6506
DOI - 10.1002/cplu.201300236
Subject(s) - wetting , self assembled monolayer , aldehyde , monolayer , dielectric spectroscopy , contact angle , arginine , hydrogen bond , materials science , chemistry , electrochemistry , nanotechnology , chemical engineering , combinatorial chemistry , organic chemistry , molecule , electrode , biochemistry , amino acid , composite material , catalysis , engineering
A new aldehyde calix[4]arene (C4AH) was synthesized efficiently to give a yield of 90 % and was used to form self‐assembled monolayers (SAMS) by means of click chemistry to give a highly selective wettability and impedance sensor for arginine (Arg). The success of the C4AH functional interface and Arg‐responsive events were confirmed by contact‐angle (CA) measurements and electrochemical impedance spectroscopy (EIS). Furthermore, the C4AH functional interface can be used as wettability‐responsive cycles at least eight times. This type of sensor operates on the principle that Arg has a high p K a value of 12.48, and is able to form strong hydrogen bonds with aldehyde selectivity, which results in a significant CA change. The proposed wettability‐sensing devices display a remarkable specificity, intuitiveness, and convenience, which should be suitable for the production of arginine recognition chips that can be used in the fields of biology and medical science.