Premium
Manganese Salen Compounds Embedded within Cross‐Linked Chiral Polyethylenimine: Asymmetric Epoxidation in an Aqueous Biphasic Medium
Author(s) -
Levi Noam,
Neumann Ronny
Publication year - 2012
Publication title -
chempluschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.801
H-Index - 61
ISSN - 2192-6506
DOI - 10.1002/cplu.201200203
Subject(s) - chemistry , polyethylenimine , manganese , aqueous medium , aqueous solution , organic chemistry , combinatorial chemistry , biochemistry , transfection , gene
Chiral cross‐linked polyethylenimines were used to intercalate Mn III salen catalysts, thereby inducing a chiral environment upon an achiral metal complex. The synzyme, dispersed in water, catalyzes the aqueous biphasic asymmetric epoxidation of styrene derivatives (see structure; L=Cl, OAc, R=isopropyl, phenyl). In the presence of the chiral catalyst there is a significant synergistic effect that increases the enantioselectivity of epoxidation.