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Single‐Stranded DNA‐Mediated Immobilization of Graphene on a Gold Electrode for Sensitive and Selective Determination of Dopamine
Author(s) -
Wang Lei,
Qin Xiaoyun,
Liu Sen,
Luo Yonglan,
Asiri Abdullah M.,
AlYoubi Abdulrahman O.,
Sun Xuping
Publication year - 2012
Publication title -
chempluschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.801
H-Index - 61
ISSN - 2192-6506
DOI - 10.1002/cplu.201100009
Subject(s) - graphene , stacking , ascorbic acid , electrode , detection limit , dopamine , dna , nanotechnology , combinatorial chemistry , selectivity , biosensor , materials science , chemistry , biochemistry , chromatography , organic chemistry , biology , catalysis , food science , neuroscience
Chemically modified electrodes : The fast and effective immobilization of graphene on a Au electrode has been demonstrated by exploiting Au–S interactions between Au and a thiolated single‐stranded DNA as well as π–π stacking interactions between graphene and DNA bases (see figure). The resultant modified electrode exhibits high sensitivity and selectivity in dopamine detection with a detection limit of 0.8 n M in the presence of ascorbic acid.