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G‐SERF Editing in Two‐Dimensional Pure‐Shift Total Correlation Spectroscopy: Scalar Coupling Measurements for a Group of Spins in Organic Molecules
Author(s) -
Rao Kakita Veera Mohana,
Joshi Mamata V,
Hosur Ramakrishna V
Publication year - 2019
Publication title -
chemphyschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.016
H-Index - 140
eISSN - 1439-7641
pISSN - 1439-4235
DOI - 10.1002/cphc.201900174
Subject(s) - spins , chemistry , scalar (mathematics) , chemical shift , spectroscopy , molecular physics , spectral line , pulse sequence , coupling (piping) , excitation , nuclear magnetic resonance spectroscopy , physics , nuclear magnetic resonance , condensed matter physics , stereochemistry , materials science , quantum mechanics , geometry , mathematics , metallurgy
A novel G‐SERF‐PSYCHE‐TOCSY (gradient encoded selective refocusing in pure shift yielded by chirp excitation version of total correlation spectroscopy) NMR pulse scheme has been proposed, which produces TOCSY chemical shift correlations, on one hand, and scalar coupling values for the spins scalarly coupled to irradiated resonances, by showing them as doublets along the indirect dimension, on the other. Therefore, recording such an experiment, for a group of spins with overlapping chemical shifts, in organic molecules can adequately provide scalar coupling information in a G‐SERF manner along the indirect dimensions, and they can be assigned to particular spin pairs. Such COSY chemical shift correlations (which appear as doublets for the scalarly coupled spins) can be readily discriminated from the TOCSY peaks (which do not show such splitting) in the G‐SERF‐PSYCHE‐TOCSY spectrum.