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Interleaved Dual NMR Acquisition of Equivalent Transfer Pathways in TOCSY and HSQC Experiments
Author(s) -
Nolis Pau,
MotiramCorral Kumar,
PérezTrujillo Míriam,
Parella Teodor
Publication year - 2019
Publication title -
chemphyschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.016
H-Index - 140
eISSN - 1439-7641
pISSN - 1439-4235
DOI - 10.1002/cphc.201801034
Subject(s) - heteronuclear single quantum coherence spectroscopy , spectral line , chemistry , two dimensional nuclear magnetic resonance spectroscopy , stereochemistry , physics , astronomy
A dual NMR data acquisition strategy to handle and detect two active equivalent transfer pathways is presented and discussed. We illustrate the power of this time‐efficient approach by collecting two different 2D spectra simultaneously in a single experiment: i) TOCSY or HSQC‐TOCSY spectra with different mixing times, ii) F2‐ 13 C‐coupled and decoupled HSQC spectra, iii) conventional and pure‐shift HSQC spectra, or iv) complementary HSQC and HSQC‐TOCSY spectra.