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Photo and Thermo Dual‐Responsive Copolymer Surfaces for Efficient Cell Capture and Release
Author(s) -
Hao Yuwei,
Liu Hongliang,
Li Guannan,
Cui Haijun,
Jiang Lei,
Wang Shutao
Publication year - 2018
Publication title -
chemphyschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.016
H-Index - 140
eISSN - 1439-7641
pISSN - 1439-4235
DOI - 10.1002/cphc.201701145
Subject(s) - copolymer , steric effects , spiropyran , materials science , isomerization , dual (grammatical number) , silicon , nanotechnology , chemical engineering , dual role , chemistry , polymer , catalysis , combinatorial chemistry , photochromism , organic chemistry , optoelectronics , composite material , engineering , art , literature
To overcome the low efficiency of single‐responsive smart surfaces, we have constructed a dual‐responsive smart surface – poly(spiropyran‐ co ‐N‐isopropylacrylamide) (poly(SP‐ co ‐NiPAAm))‐grafted silicon nanowire arrays – by combining photo‐responsive SP and thermo‐responsive NiPAAm units for enhancing the efficiencies of cancer‐cell capture and release. These enhanced efficiencies probably originate from the binary cooperative effect of two responsive building units: NiPAAm units can decrease the steric hindrance between SP units during the isomerization while SP units can facilitate phase transition of NiPAAm units. This study provides a new strategy for designing smart materials and surfaces with efficient responsiveness for biomedical applications.