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Front Cover: Role of the Chalcogen (S, Se, Te) in the Oxidation Mechanism of the Glutathione Peroxidase Active Site (ChemPhysChem 21/2017)
Author(s) -
Bortoli Marco,
Torsello Mauro,
Bickelhaupt F. Matthias,
Orian Laura
Publication year - 2017
Publication title -
chemphyschem
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.016
H-Index - 140
eISSN - 1439-7641
pISSN - 1439-4235
DOI - 10.1002/cphc.201701129
Subject(s) - front cover , active site , peroxidase , chemistry , chalcogen , glutathione peroxidase , selenium , cover (algebra) , glutathione , biochemistry , enzyme , crystallography , organic chemistry , mechanical engineering , engineering
The Front Cover displays GPx active sites as lightning bolts during a thunderstorm (S and Te mutants), and during a clear night for Sec‐GPx, associating its much higher anti‐oxidant power to the tremendously powerful positive lightning bolts. In their Full Paper, M. Bortoli et al. elucidate oxidation by H 2 O 2 occurring in the active site of glutathione peroxidases (GPx) in silico. More information can be found in the Full Paper by M. Bortoli et al on page 2990 in Issue 21, 2017 (DOI: 10.1002/cphc.201700743).