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Deuteration of Hyperpolarized 13 C‐Labeled Zymonic Acid Enables Sensitivity‐Enhanced Dynamic MRI of pH
Author(s) -
Hundshammer Christian,
Düwel Stephan,
Köcher Simone S.,
Gersch Malte,
Feuerecker Benedikt,
Scheurer Christoph,
Haase Axel,
Glaser Steffen J.,
Schwaiger Markus,
Schilling Franz
Publication year - 2017
Publication title -
chemphyschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.016
H-Index - 140
eISSN - 1439-7641
pISSN - 1439-4235
DOI - 10.1002/cphc.201700956
Subject(s) - deuterium , nuclear magnetic resonance , chemistry , front cover , in vivo , nuclear magnetic resonance spectroscopy , hyperpolarization (physics) , cover (algebra) , analytical chemistry (journal) , physics , chromatography , nuclear physics , mechanical engineering , microbiology and biotechnology , engineering , biology
The front cover artwork is provided by the groups of Dr. Christoph Scheurer, Prof. Axel Haase, Prof. Steffen J. Glaser, Prof. Markus Schwaiger and Dr. Franz Schilling from Technical University of Munich. The image shows deuterated zymonic acid, its pH‐sensitive 13 C NMR resonances and examples of how this sensor can be used to non‐invasively image pH both in vitro and in vivo. Read the full text of the article at 10.1002/cphc.201700779.