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Cover Picture: Pressure—A Gateway to Fundamental Insights into Protein Solvation, Dynamics, and Function (ChemPhysChem 17/2015)
Author(s) -
Luong Trung Quan,
Kapoor Shobhna,
Winter Roland
Publication year - 2015
Publication title -
chemphyschem
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.016
H-Index - 140
eISSN - 1439-7641
pISSN - 1439-4235
DOI - 10.1002/cphc.201501004
Subject(s) - energy landscape , solvation , free energy perturbation , cover (algebra) , molecular dynamics , gateway (web page) , chemistry , protein dynamics , biophysics , nanotechnology , computational chemistry , biology , computer science , materials science , biochemistry , world wide web , engineering , mechanical engineering , solvent
Pressure perturbation serves as an important physicochemical tool to explore the free energy and conformational landscape of proteins. From shaping the free‐energy landscape of proteins themselves to that of their interactions, conformational fluctuations not only dictate a plethora of biological processes, but are also implicated in a number of debilitating diseases. More details can be found in the Minireview by R. Winter et al. on page 3555 in Issue 17, 2015 (DOI: 10.1002/cphc.201500669).