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Cationic Porphyrin–Anionic Surfactant Mixtures for the Promotion of Self‐Organized 1:4 Ion Pairs in Water with Strong Aggregation Properties
Author(s) -
Pradines Vincent,
Bijani Christian,
Stigliani JeanLuc,
Blanzat Muriel,
RicoLattes Isabelle,
Pratviel Geneviève
Publication year - 2015
Publication title -
chemphyschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.016
H-Index - 140
eISSN - 1439-7641
pISSN - 1439-4235
DOI - 10.1002/cphc.201500783
Subject(s) - porphyrin , cationic polymerization , chemistry , micelle , supramolecular chemistry , aqueous solution , pulmonary surfactant , alkyl , stoichiometry , aggregation number , j aggregate , amphiphile , self assembly , polymer chemistry , inorganic chemistry , chemical engineering , critical micelle concentration , organic chemistry , molecule , polymer , copolymer , biochemistry , engineering
We performed a systematic study on the spectroscopic and aggregation properties of stoichiometric mixtures (1:4) of the tetracationic meso ‐tetrakis(4‐ N ‐methylpyridinium)porphyrin (H 2 TMPyP) and three sodium alkylsulfate surfactants (tetradecyl, hexadecyl, and octadecylsulfate) in an aqueous solution. The objective was to build a supramolecular aggregate, which would favor the internalization of tetracationic porphyrins in cells without chemical modification of the structure of the porphyrin. We show that stoichiometric H 2 TMPyP/alkylsulfate (1:4) mixtures lead to the formation of large hollow spherical aggregates (60–160 nm). The TEM images show that the membrane of these aggregates are composed of smaller aggregates, which are probably rod‐like micelles. These rod‐like micelles have a hydrophobic core composed of the alkyl chains of the alkylsulfate surfactant, whereas the charged surface corresponds to the tetracationic porphyrins.