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Fast Gradient‐Encoded CEST Spectroscopy of Hyperpolarized Xenon
Author(s) -
Döpfert Jörg,
Witte Christopher,
Schröder Leif
Publication year - 2014
Publication title -
chemphyschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.016
H-Index - 140
eISSN - 1439-7641
pISSN - 1439-4235
DOI - 10.1002/cphc.201300888
Subject(s) - xenon , nuclear magnetic resonance , flip angle , chemistry , isotopes of xenon , spectroscopy , nuclear magnetic resonance spectroscopy , signal (programming language) , hyperpolarization (physics) , physics , atomic physics , magnetic resonance imaging , computer science , quantum mechanics , programming language , medicine , radiology
Breaking speed limits: The acquisition of xenon‐129 Hyper‐CEST spectra is drastically accelerated by utilizing gradients to encode the chemical shift dimension (see picture). The signal is increased by using repeated spin‐echo refocussing. The additional application of a variable flip angle makes the experiment independent from a constant Xe redelivery.