Premium
Excimer Formation by Stacking G‐Quadruplex Blocks
Author(s) -
Dao Nguyen Thuan,
Haselsberger Reinhard,
MichelBeyerle MariaElisabeth,
Phan Anh Tuân
Publication year - 2013
Publication title -
chemphyschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.016
H-Index - 140
eISSN - 1439-7641
pISSN - 1439-4235
DOI - 10.1002/cphc.201300481
Subject(s) - stacking , g quadruplex , sequence (biology) , computer science , stack (abstract data type) , excimer , dimer , guanine , chemistry , nanotechnology , information retrieval , dna , materials science , fluorescence , nucleotide , physics , optics , operating system , biochemistry , organic chemistry , gene
A special stack: In the presence of K + ions, a specific guanine‐rich DNA sequence forms a stacked G‐quadruplex dimer giving rise to excimer emission in the 400 nm region. This emission with nanosecond lifetime occurs only for a particular base overlap pattern between two stacked G‐quadruplex blocks and can be manipulated by changing DNA sequence and external conditions.