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Bioactive Formulations with Sugar‐Derived Surfactants: A New Approach for Photoprotection and Controlled Release of Promethazine
Author(s) -
Bize Cécile,
Garrigues JeanChristophe,
Corbet JeanPierre,
RicoLattes Isabelle,
Blanzat Muriel
Publication year - 2013
Publication title -
chemphyschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.016
H-Index - 140
eISSN - 1439-7641
pISSN - 1439-4235
DOI - 10.1002/cphc.201200932
Subject(s) - photoprotection , photodegradation , promethazine , chemistry , drug delivery , controlled release , phloroglucinol , sugar , drug , micelle , excipient , drug carrier , chromatography , nanotechnology , organic chemistry , materials science , pharmacology , biochemistry , medicine , photosynthesis , photocatalysis , aqueous solution , catalysis
Skin deep: A bioactive formulation for dermal delivery of antihistamines is obtained by using the original properties of catanionic associations towards self‐assembly in water. The drug, which participates in its own transport, is preserved from photodegradation when solubilised in the bioactive formulation. The drug release through the skin is also delayed.