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Peptide–Surface Adsorption Free Energy Comparing Solution Conditions Ranging from Low to Medium Salt Concentrations
Author(s) -
Wei Yang,
Thyparambil Aby A.,
Latour Robert A.
Publication year - 2012
Publication title -
chemphyschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.016
H-Index - 140
eISSN - 1439-7641
pISSN - 1439-4235
DOI - 10.1002/cphc.201200527
Subject(s) - adsorption , monolayer , peptide , chemistry , phosphate buffered saline , surface plasmon resonance , salt (chemistry) , characterization (materials science) , desorption , spectroscopy , phosphate , analytical chemistry (journal) , nanotechnology , chemical engineering , chromatography , materials science , organic chemistry , nanoparticle , physics , biochemistry , quantum mechanics , engineering
Multi‐technique methods involving surface plasmon resonance spectroscopy and atomic force microscopy provide experimental data for the characterization of peptide adsorption on self‐assembled monolayers. A comparative study is carried out in phosphate‐buffered saline (PBS) and potassium phosphate‐buffered (PPB) water to determine the influence of the salt concentration on the adsorption behavior (see figure; Δ G 0 ads : free energy of peptide adsorption, F des : force required for peptide desorption).