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UFJCOSY: A Fast 3D NMR Method for Measuring Isotopic Enrichments in Complex Samples
Author(s) -
Giraudeau Patrick,
Cahoreau Edern,
Massou Stéphane,
Pathan Meerakhan,
Portais JeanCharles,
Akoka Serge
Publication year - 2012
Publication title -
chemphyschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.016
H-Index - 140
eISSN - 1439-7641
pISSN - 1439-4235
DOI - 10.1002/cphc.201200255
Subject(s) - chemistry , carbon 13 nmr , isotopic labeling , nuclear magnetic resonance spectroscopy , ultrashort pulse , analytical chemistry (journal) , chromatography , organic chemistry , physics , laser , optics
A fast 3D NMR method is described (see picture), which gives access to site‐specific 13 C isotopic enrichments in complex biological mixtures in a few minutes. It relies on a hybrid strategy combining ultrafast and conventional 2D NMR acquisition techniques.