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Structural Studies on Ionic Liquid/Water/Peptide Systems by HR‐MAS NMR Spectroscopy
Author(s) -
MrestaniKlaus Carmen,
Richardt Annekathrin,
Wespe Christian,
Stark Annegret,
Humpfer Eberhard,
Bordusa Frank
Publication year - 2012
Publication title -
chemphyschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.016
H-Index - 140
eISSN - 1439-7641
pISSN - 1439-4235
DOI - 10.1002/cphc.201100927
Subject(s) - ionic liquid , chemistry , magic angle spinning , nuclear magnetic resonance spectroscopy , aqueous solution , spectroscopy , ionic bonding , peptide , nmr spectra database , analytical chemistry (journal) , nuclear magnetic resonance , spectral line , chromatography , organic chemistry , ion , catalysis , biochemistry , physics , quantum mechanics , astronomy
The present work reports on an assessment of high‐resolution magic angle spinning (HR‐MAS) NMR spectroscopy for structural investigations of peptides dissolved in aqueous ionic liquids. Highly resolved one‐ and two‐dimensional NMR spectra are obtained that allow for complete proton resonance assignments of both the peptides as solutes and the ionic liquids as solvents. Successful application of the HR‐MAS method facilitates for the first time high‐resolution NMR analysis of complex ionic liquid/peptide systems at the molecular level, mainly on the basis of chemical‐shift changes.