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Dynamic Enantiodivergent Organocatalysis: Merging Molecular Motors with Bifunctional Organocatalysts
Author(s) -
Sohtome Yoshihiro,
Nagasawa Kazuo
Publication year - 2011
Publication title -
chemphyschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.016
H-Index - 140
eISSN - 1439-7641
pISSN - 1439-4235
DOI - 10.1002/cphc.201100335
Subject(s) - organocatalysis , bifunctional , enantioselective synthesis , enantiomer , chemistry , catalysis , organic chemistry , stereochemistry
A basic strategy reported by Wang and Feringa for enantiodivergent organocatalysis by exploiting the dynamic stereochemical changes of a molecular motor is described herein. Unidirectional switching of the organocatalytic system can be triggered in situ to produce a racemate, one enantiomer or the other enantiomer of the product of a catalytic carbon–sulfur bond‐forming process.