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Triple Resonance Cross‐Polarization for More Sensitive 13 C MAS NMR Spectroscopy of Deuterated Proteins
Author(s) -
Akbey Ümit,
Camponeschi Francesca,
van Rossum BarthJan,
Oschkinat Hartmut
Publication year - 2011
Publication title -
chemphyschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.016
H-Index - 140
eISSN - 1439-7641
pISSN - 1439-4235
DOI - 10.1002/cphc.201100084
Subject(s) - deuterium , nuclear magnetic resonance spectroscopy , chemistry , spectroscopy , polarization (electrochemistry) , nuclear magnetic resonance , deuterium nmr , analytical chemistry (journal) , stereochemistry , atomic physics , organic chemistry , physics , quantum mechanics
Save the last WALTZ for me: The use of simultaneous proton and deuterium cross‐polarization for 13 C CPMAS NMR spectroscopy in highly deuterated proteins is discussed. The aim of the new method introduced herein, triple‐resonance cross‐polarization, is to increase the sensitivity of the carbon‐detected methods in such systems (see picture).