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Nanoscale Patterning of Multicomponent Proteins by Bias‐Assisted Atomic Force Microscopy Nanolithography
Author(s) -
Xing Chunyan,
Zheng Zhikun,
Zhang Bailin,
Tang Jilin
Publication year - 2011
Publication title -
chemphyschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.016
H-Index - 140
eISSN - 1439-7641
pISSN - 1439-4235
DOI - 10.1002/cphc.201100026
Subject(s) - nanolithography , nanotechnology , ethylene glycol , atomic force microscopy , nanoscopic scale , dip pen nanolithography , aptamer , microscopy , materials science , nanostructure , chemistry , fabrication , optics , pathology , medicine , alternative medicine , physics , organic chemistry , biology , genetics
Well‐assisted nanopatterns: A new route to fabricate multicomponent protein nanopatterns by combining bias‐assisted atomic force microscopy nanolithography and aptamer–protein recognition is presented. Two types of aptamer arrays for anchoring platelet‐derived growth‐factor‐BB and thrombin (see picture) are introduced [Eg3‐SH: 11‐mercaptoundecyl‐tri(ethylene glycol)].