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Fibrinogen Nanofibril Growth and Self‐Assembly on Au (1,1,1) Surface in the Absence of Thrombin
Author(s) -
Chen Guojun,
Ni Nanting,
Wang Binghe,
Xu Bingqian
Publication year - 2010
Publication title -
chemphyschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.016
H-Index - 140
eISSN - 1439-7641
pISSN - 1439-4235
DOI - 10.1002/cphc.200900916
Subject(s) - adsorption , thrombin , nanotechnology , thrombin generation , self assembly , fibrinogen , surface (topology) , chemistry , coagulation , materials science , crystallography , platelet , biochemistry , biology , psychology , geometry , mathematics , psychiatry , immunology
Gold self‐assembly: Understanding protein adsorption on gold surface bears increasing importance because of surface‐induced changes in conformation and bioactivity. Nanofibril structures of protein fibrinogen (fg) molecules, playing paramount role in blood coagulation, are found self‐assembled on a Au(1,1,1) surface without any addition of thrombin, growing in two orientations (longitude and transverse, see figure).