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A Self‐assembly Route for Double Bilayer Lipid Membrane Formation
Author(s) -
Han Xiaojun,
Achalkumar Ammathnadu S.,
Cheetham Matthew R.,
Connell Simon D. A.,
Johnson Benjamin R. G.,
Bushby Richard J.,
Evans Stephen D.
Publication year - 2010
Publication title -
chemphyschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.016
H-Index - 140
eISSN - 1439-7641
pISSN - 1439-4235
DOI - 10.1002/cphc.200900798
Subject(s) - lipid bilayer , membrane , bilayer , chemistry , model lipid bilayer , membrane protein , biological membrane , nanotechnology , lipid bilayer phase behavior , biophysics , materials science , biochemistry , biology
Biomembranes: A new method of forming double bilayer lipid membranes uses NHS/EDC chemistry to link adjacent bilayers, both of which remain fluid. This approach provides a novel platform for the study of biomembranes, in which the components of the upper membrane are shielded from the solid substrate by a second membrane (see figure); and for studying more complex membrane protein systems which span double lipid bilayers.