Premium
Graphene on Au(111): A Highly Conductive Material with Excellent Adsorption Properties for High‐Resolution Bio/Nanodetection and Identification
Author(s) -
Song Bo,
Li Di,
Qi Wenpeng,
Elstner Marcus,
Fan Chunhai,
Fang Haiping
Publication year - 2010
Publication title -
chemphyschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.016
H-Index - 140
eISSN - 1439-7641
pISSN - 1439-4235
DOI - 10.1002/cphc.200900743
Subject(s) - graphene , stacking , biomolecule , biosensor , materials science , conductivity , substrate (aquarium) , adsorption , nanotechnology , nucleobase , carbon fibers , molecule , chemistry , dna , composite number , composite material , organic chemistry , biochemistry , oceanography , geology
Based on numerical simulations and experimental studies, we show that a composite material which consists of a sheet of graphene on a Au(111) surface exhibits both an excellent conductivity and the ability to stably adsorb biomolecules. If we use this material as a substrate, the signal‐to‐noise ratios can be greatly enhanced. The key to this unique property is that graphene can stably adsorb carbon‐based rings, which are widely present in biomolecules, due to π‐stacking interactions while the substrate retains the excellent conductivity of gold. Remarkably, the signal‐to‐noise ratio is found to be so high that the signal is clearly distinguishable for different nucleobases when an ssDNA is placed on this graphene‐on‐Au(111) material. Our finding opens opportunities for a range of bio/nano‐applications including single‐DNA‐molecule‐based biodevices and biosensors, particularly, high‐accuracy sequencing of DNA strands with repeating segments.