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Evidence for Interleaflet Slip During Spreading of Single Lipid Bilayers at Hydrophilic Solids
Author(s) -
Sanii Babak,
Nguyen Kathy,
Rädler Joachim O.,
Parikh Atul N.
Publication year - 2009
Publication title -
chemphyschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.016
H-Index - 140
eISSN - 1439-7641
pISSN - 1439-4235
DOI - 10.1002/cphc.200900372
Subject(s) - slip (aerodynamics) , lipid bilayer , membrane , chemistry , nanotechnology , chemical physics , optics , materials science , physics , thermodynamics , biochemistry
Membrane dynamics: Slip—the relative mobility of the two leaflets in lipid bilayers—represents a generic mechanical‐dynamical process. To establish the presence of interleaflet slip in the surface‐spreading lipid membranes, the advancing lipid bilayers are exposed to an intense laser spot, which rapidly bleaches the illuminated fluorophores in a radially symmetric shape (see figure).