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DNA Molecules on GaP (100) Surfaces: Spectroscopic Characterization and Biospecificity Assessment
Author(s) -
FloresPerez Rosangelly,
Zemlyanov Dmitry Y.,
Ivanisevic Albena
Publication year - 2008
Publication title -
chemphyschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.016
H-Index - 140
eISSN - 1439-7641
pISSN - 1439-4235
DOI - 10.1002/cphc.200800166
Subject(s) - streptavidin , fluorophore , substrate (aquarium) , molecule , dna , characterization (materials science) , chemistry , alkyl , conjugate , nanotechnology , combinatorial chemistry , nanoparticle , biotin , materials science , fluorescence , organic chemistry , biochemistry , physics , biology , optics , ecology , mathematical analysis , mathematics
Mind the bioactive GaP: Carboxylic acid‐terminated GaP(100) surfaces are used to capture DNA molecules. The well‐packed mixed biotin‐modified DNA and alkyl‐chains self‐assemble onto the substrate (see figure) and exhibit good reproducibility, specificity and bioactivity confirmed by the use of nanoparticles and Cy3 fluorophore conjugates with streptavidin.