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Cover Picture: Effect of Gramicidin on Phospholipid‐Modified Monolayers and on Ion Transfer at a Liquid–Liquid Interface (ChemPhysChem 6/2007)
Author(s) -
Santos Hélder A.,
Carlsson Sanna,
Murtomäki Lasse,
Kontturi Kyösti
Publication year - 2007
Publication title -
chemphyschem
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.016
H-Index - 140
eISSN - 1439-7641
pISSN - 1439-4235
DOI - 10.1002/cphc.200790013
Subject(s) - monolayer , gramicidin , chemistry , cyclic voltammetry , phospholipid , ities , membrane , analytical chemistry (journal) , biological membrane , organic chemistry , electrochemistry , electrode , biochemistry
The cover picture shows a gramicidin embedded biomembrane that interacts with dextran sulfate (DS). These interactions affect drug transfer across the liquid–liquid interface. Langmuir–Blodgett and voltammetry techniques are used to study the interfacial and physicochemical properties of the system. A detailed characterization of the monolayers is presented, and drug transfer is discussed as a result of the modified surface charge and compactness of the lipid in the presence of gramicidin, calcium and DS. Further details can be found in the Article by H. A. Santos et al. on page 913.