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Thermodynamic Properties of Duplex DNA in Microchannel Laminar Flow
Author(s) -
Yamashita Kenichi,
Miyazaki Masaya,
Yamaguchi Yoshiko,
Nakamura Hiroyuki,
Maeda Hideaki
Publication year - 2007
Publication title -
chemphyschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.016
H-Index - 140
eISSN - 1439-7641
pISSN - 1439-4235
DOI - 10.1002/cphc.200700152
Subject(s) - microchannel , microreactor , laminar flow , duplex (building) , chemistry , circular dichroism , microfluidics , thermodynamics , nanotechnology , crystallography , materials science , dna , physics , organic chemistry , biochemistry , catalysis
Microreactor: Linear dichroism and UV‐thermal measurements of duplex DNAs in a continuous‐flow microchannel system are presented and the results compared to those from batchwise labscale systems. The observed shift in thermal stability is induced by the conformational change under shear stress (see figure).