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Cover Picture: Combined AFM and Two‐Focus SFCS Study of Raft‐Exhibiting Model Membranes (ChemPhysChem 11/2006)
Author(s) -
Chiantia Salvatore,
Ries Jonas,
Kahya Nicoletta,
Schwille Petra
Publication year - 2006
Publication title -
chemphyschem
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.016
H-Index - 140
eISSN - 1439-7641
pISSN - 1439-4235
DOI - 10.1002/cphc.200690035
Subject(s) - atomic force microscopy , raft , lipid bilayer , lipid raft , nanoscopic scale , nanotechnology , focus (optics) , microscopy , materials science , lateral diffusion , force spectroscopy , membrane , biological membrane , scanning probe microscopy , biophysics , chemistry , optics , biology , physics , polymer , biochemistry , copolymer , composite material
The cover picture shows the simultaneous application of atomic force microscopy (AFM), laser scanning microscopy (LSM) and two‐focus scanning fluorescence spectroscopy (SFCS) on a model membrane of biological relevance. While structural data is provided by the nanoscopic spatial resolution of the AFM, 2‐focus SFCS can be used to probe the diffusion of proteins and lipids in distinct microdomains of the lipid bilayer. In the article on page 2409, S. Chiantia and J. Ries et al. show that the lateral organization of lipid and proteins can be reliably probed by the combined approach of these techniques.