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Single‐Molecule Conductance Measurements of Single‐ and Double‐Stranded DNA Oligonucleotides
Author(s) -
van Zalinge Harm,
Schiffrin David J.,
Bates Andrew D.,
Haiss Wolfgang,
Ulstrup Jens,
Nichols Richard J.
Publication year - 2006
Publication title -
chemphyschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.016
H-Index - 140
eISSN - 1439-7641
pISSN - 1439-4235
DOI - 10.1002/cphc.200500413
Subject(s) - conductance , stacking , molecule , oligonucleotide , dna , scanning tunneling microscope , chemistry , quantum tunnelling , base pair , chemical physics , crystallography , nanotechnology , materials science , biochemistry , physics , condensed matter physics , optoelectronics , organic chemistry
Charge transfer through DNA : The single‐molecule conductance of homopolymeric oligodeoxynucleotides has been recorded using scanning tunneling microscopy. The conductance σ of these oligodeoxynucleotides is very low when compared to double‐stranded molecules. This clearly illustrates the importance of base stacking for conductance in double strands. The conductance values for single‐stranded oligodeoxynucleotides do, however, depend on the identity of the base (see picture).