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Equilibrium Coverage Fluctuations: A New Approach to Quantify Reversible Adsorption of Proteins
Author(s) -
Lüthgens Eike,
Janshoff Andreas
Publication year - 2005
Publication title -
chemphyschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.016
H-Index - 140
eISSN - 1439-7641
pISSN - 1439-4235
DOI - 10.1002/cphc.200400446
Subject(s) - adsorption , monte carlo method , desorption , chemistry , kinetics , content (measure theory) , equilibrium constant , statistical physics , computer science , physics , statistics , mathematics , mathematical analysis , quantum mechanics
Binding kinetics of proteins on sensor devices : A new approach to simultaneously determine the rate constants of adsorption and desorption of proteins on surfaces at low coverage from the power spectrum of equilibrium coverage fluctuations is proposed and verified by dynamic Monte Carlo simulations (see picture).