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A New Cubic Phase Containing DNA and a Surfactant
Author(s) -
McLoughlin Daragh,
ImpérorClerc Marianne,
Langevin Dominique
Publication year - 2004
Publication title -
chemphyschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.016
H-Index - 140
eISSN - 1439-7641
pISSN - 1439-4235
DOI - 10.1002/cphc.200400163
Subject(s) - pulmonary surfactant , dna , cationic polymerization , phase (matter) , micelle , chemical engineering , materials science , rod , chemistry , crystallography , nanotechnology , polymer chemistry , organic chemistry , biochemistry , aqueous solution , medicine , alternative medicine , pathology , engineering
Encapsulating DNA: A new cubic phase that contains both DNA and a cationic surfactant was discovered. The authors propose a cubic arrangement of surfactant micelles with DNA rods intercalated between several cells (see picture). The results presented here may be important for the development of efficient delivery vectors for genetic material.