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System‐Size Biresonance for Intracellular Calcium Signaling
Author(s) -
Zhang Jiqian,
Hou Zhonghuai,
Xin Houwen
Publication year - 2004
Publication title -
chemphyschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.016
H-Index - 140
eISSN - 1439-7641
pISSN - 1439-4235
DOI - 10.1002/cphc.200400089
Subject(s) - calcium , intracellular , chemistry , calcium signaling , calcium in biology , biophysics , microbiology and biotechnology , biochemistry , biology , organic chemistry
Using the chemical Langevin equation , the authors have addressed the effects of internal fluctuations on intracellular calcium signaling. It is found that the effect of the internal fluctuations depends on the volume of the cell. The signal‐to‐noise ratio (SNR; see plot) of the stochastic calcium oscillation shows two maxima, demonstrating the occurrence of system‐size biresonance. Most importantly, the first resonance matches the size of real living cells.