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Cover Picture: Freely Suspended Actin Cortex Models on Arrays of Microfabricated Pillars (ChemPhysChem 8/2003)
Author(s) -
Roos Wouter H.,
Roth Alexander,
Konle Johannes,
Presting Hartmut,
Sackmann Erich,
Spatz Joachim P.
Publication year - 2003
Publication title -
chemphyschem
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.016
H-Index - 140
eISSN - 1439-7641
pISSN - 1439-4235
DOI - 10.1002/cphc.200390091
Subject(s) - filamin , actin , materials science , cover (algebra) , fluorescence , nanotechnology , biophysics , chemistry , optics , cytoskeleton , biology , cell , physics , biochemistry , engineering , mechanical engineering
The cover picture shows the first demonstration of a biomimetic model of the cellular actin cortex. The actin filamental network imaged as a fluorescent micrograph (orange) is suspended on top of an array of microfabricated silicon pillars, schematically drawn in light blue. The actin network is obtained by polymerising actin filaments from a template provided by gold‐capped pillars. Subsequently adding filamin as actin‐crosslinking protein causes the formation of the ordered network within minutes. Find out more in the article by Spatz and co‐workers on pages 872–877.