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Noncontact Surface Force Microscopy of Protein Molecules
Author(s) -
Aoki Takaaki,
Sowa Yoshiyuki,
Yanagida Toshio
Publication year - 2003
Publication title -
chemphyschem
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.016
H-Index - 140
eISSN - 1439-7641
pISSN - 1439-4235
DOI - 10.1002/cphc.200300796
Subject(s) - stylus , electrostatic force microscope , scanning force microscopy , nanometre , microscopy , atomic force microscopy , intermolecular force , molecule , surface forces apparatus , electrostatics , chemistry , magnetic force microscope , kelvin probe force microscope , nanotechnology , scanning probe microscopy , analytical chemistry (journal) , materials science , optics , physics , composite material , magnetization , chromatography , organic chemistry , quantum mechanics , magnetic field , acoustics
Using intermolecular force microscopy , the forces in the sub‐piconewton order between the probe stylus and the sample surfaces can be measured with a gap distance controlled with nanometer accuracy. In this study, electrostatic features of the protein surface were visualized as 2D electrostatic force maps (see picture). Furthermore, the interaction between motor proteins in the noncontact region was measured.