Open AccessPeripheral T ‐cell lymphoma of the oral cavity: A case report
Author(s) -
Asadi Amir Ali,
Mahmoudi Hamed,
Mofidi Abbas,
Mortezazadeh Masoud,
Hadizadeh Alireza
Publication year - 2023
Publication title -
cancer reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 5
ISSN - 2573-8348
DOI - 10.1002/cnr2.1751
Subject(s) - medicine , lymphoma , peripheral t cell lymphoma , lesion , differential diagnosis , chemotherapy , radiation therapy , t cell lymphoma , oral cavity , immunohistochemistry , buccal mucosa , buccal administration , pathology , large cell , stage (stratigraphy) , peripheral , not otherwise specified , immune system , t cell , radiology , cancer , immunology , paleontology , adenocarcinoma , orthodontics , biology , pharmacology
Background Peripheral T‐Cell Lymphoma Not Otherwise Specified (PTCL‐NOS) is a rare type of non‐Hodgkin T‐cell lymphoma which frequently seen in immunocompromised individuals. It is estimated that only 2% of lymphomas are located on the buccal mucosa. In this case report, we present a 34‐year‐old male with a PTCL diagnosis. Case A 34‐year‐old immune‐competent male presented with a buccal progressive ulcerated lesion. Histopathologic and immunohistochemical findings were compatible with PTCL‐NOS and classified as stage IIEA according to the Ann Arbor staging. The patient underwent chemotherapy followed by radiotherapy. He remained disease‐free after 12 months of follow‐up. Conclusion Although lymphoma is uncommon in the oral cavity, physicians especially dentists in ordinary dental checkups should consider persistent progressive lesions as an important differential diagnosis of lymphoma.