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Cover Feature: Two‐Photon Fluorescence Imaging and Therapy of Cancer Cells with Anisotropic Gold‐Nanoparticle‐Supported Porous Silicon Nanostructures (ChemNanoMat 4/2018)
Author(s) -
Chaix Arnaud,
Rajoua Khalil,
Stojanovic Vanja,
El Cheikh Khaled,
Bouffard Elise,
Brocéro Anthony,
Garcia Marcel,
Maynadier Marie,
Morère Alain,
GaryBobo Magali,
Favier Frédéric,
Durand JeanOlivier,
Cunin Frédérique
Publication year - 2018
Publication title -
chemnanomat
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.947
H-Index - 32
ISSN - 2199-692X
DOI - 10.1002/cnma.201800080
Subject(s) - photodynamic therapy , colloidal gold , porous silicon , materials science , two photon excitation microscopy , nanotechnology , nanoparticle , fluorescence , silicon , nanostructure , singlet oxygen , biophysics , optoelectronics , chemistry , optics , oxygen , physics , organic chemistry , biology
Porous silicon nanovectors carrying gold nanoparticles and functionalized with mannose species as tumor targeting agents demonstrate remarkable capability as 2‐photon imaging contrast agents. An important photodynamic efficiency of the nanovectors is also observed in human breast cancer cells, with the formation of reactive oxygen species when exposed to two‐photon light excitation. Such targeted porous silicon/gold nanovectors provide an interesting opportunity for 2‐photon imaging and for photodynamic therapy, and an interesting potential for theranostic applications. More information can be found in the Communication by Frédérique Cunin et al. on page 343 in Issue 4, 2018 (DOI: 10.1002/cnma.201700368).