Premium
From medical images to flow computations without user‐generated meshes
Author(s) -
Dillard Seth I.,
Mousel John A.,
Shrestha Liza,
Raghavan Madhavan L.,
Vigmostad Sarah C.
Publication year - 2014
Publication title -
international journal for numerical methods in biomedical engineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.741
H-Index - 63
eISSN - 2040-7947
pISSN - 2040-7939
DOI - 10.1002/cnm.2644
Subject(s) - polygon mesh , computer science , mesh generation , computation , computational science , flow (mathematics) , cartesian coordinate system , domain (mathematical analysis) , parallel computing , image processing , image (mathematics) , computer graphics (images) , algorithm , theoretical computer science , computer vision , geometry , mathematics , finite element method , mathematical analysis , physics , thermodynamics
SUMMARY Biomedical flow computations in patient‐specific geometries require integrating image acquisition and processing with fluid flow solvers. Typically, image‐based modeling processes involve several steps, such as image segmentation, surface mesh generation, volumetric flow mesh generation, and finally, computational simulation. These steps are performed separately, often using separate pieces of software, and each step requires considerable expertise and investment of time on the part of the user. In this paper, an alternative framework is presented in which the entire image‐based modeling process is performed on a Cartesian domain where the image is embedded within the domain as an implicit surface. Thus, the framework circumvents the need for generating surface meshes to fit complex geometries and subsequent creation of body‐fitted flow meshes. Cartesian mesh pruning, local mesh refinement, and massive parallelization provide computational efficiency; the image‐to‐computation techniques adopted are chosen to be suitable for distributed memory architectures. The complete framework is demonstrated with flow calculations computed in two 3D image reconstructions of geometrically dissimilar intracranial aneurysms. The flow calculations are performed on multiprocessor computer architectures and are compared against calculations performed with a standard multistep route. Copyright © 2014 John Wiley & Sons, Ltd.