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Organization of the efferent projections from the pontine parabrachial area to the bed nucleus of the stria terminalis and neighboring regions: A PHA‐L study in the rat
Author(s) -
Alden Marie,
Besson JeanMarie,
Bernard JeanFrançois
Publication year - 1994
Publication title -
journal of comparative neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.855
H-Index - 209
eISSN - 1096-9861
pISSN - 0021-9967
DOI - 10.1002/cne.903410302
Subject(s) - stria terminalis , substantia innominata , parabrachial nucleus , anatomy , lateral hypothalamus , globus pallidus , zona incerta , biology , efferent , medial forebrain bundle , neuroscience , lateral parabrachial nucleus , septal nuclei , hypothalamus , preoptic area , periaqueductal gray , nucleus , basal forebrain , striatum , central nervous system , basal ganglia , midbrain , afferent , dopamine
The organization of efferent projections from the pontine parabrachial (pPB) area to the forebrain rostral to the central nucleus of the amygdala (Ce) was studied in the rat by using microinjections of Phaseolus vulgaris leucoagglutinin (PHA‐L), into subregions of the pPB area. The present study is a follow‐up of a former study (Bernard et al. [1993] J. Comp. Neurol. 329:201–229) which examines pPB projections onto the Ce. The results demonstrate that: (1) the pPB(m) region (the medial, the ventral lateral subnuclei and the waist area) diffusely projects to the lateral division (BSTL) of the bed nucleus of the stria terminalis (BST), the Ce‐BSTL continuum (including, the dorsal portion of substantia innominata, the ventral portion of globus pallidus, the fundus striatum, and the substriatal area) and to a lesser extent the agranular insular cortex; (2) the pPB(1) region [the central lateral (pPBc1) and the outer portion of external lateral subnuclei] densely projects to the dorsal lateral subnucleus of BST (BSTdl); only the pPBcl subnucleus projects to the median, the anteroventral and the periventricular nuclei of the preoptic hypothalamus; and (3) the remaining pPB area (the dorsal lateral, part of the external lateral and the external medial subnuclei) projects to the nucleus of horizontal limb of diagonal band but does not project onto the BST and the preoptic hypothalamus. It is suggested that the pPB(m)‐BSTL “diffuse pathway” is mainly implicated in motivational and autonomic aspects of taste. The pPB(1)‐BSTdl and hypothalamic “concentrated pathways” could be implicated in autonomic and nociceptive processes.