Premium
Neuropeptide Y‐like immunoreactivity in the diencephalon of the little brown bat ( Myotis lucifugus ): Localized variations with physiological state
Author(s) -
Laemle Lois K.,
Cotter John R.
Publication year - 1992
Publication title -
journal of comparative neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.855
H-Index - 209
eISSN - 1096-9861
pISSN - 0021-9967
DOI - 10.1002/cne.903160405
Subject(s) - myotis lucifugus , diencephalon , biology , stria terminalis , hypothalamus , suprachiasmatic nucleus , medial forebrain bundle , median eminence , anatomy , zona incerta , supraoptic nucleus , forebrain , nucleus , endocrinology , medicine , neuroscience , central nervous system , striatum , ecology , dopamine
The current study used light microscopic immunocytochemistry to demonstrate and compare neuropeptide Y‐like immunoreactivity (NPY‐IR) in the diencephalon of the little brown bat ( Myotis lucifugus ) at different stages in its annual cycle of activity and hibernation. Animals were sacrificed in each of three discrete physiological states: euthermic, hypothermic, and hibernating. In general, NPY‐IR was abundant in the hypothalamus and sparse in other diencephalic areas. Immunoreactivity was present in a number of pathways which project to or originate from diencephalic nuclei; these include the ansa peduncularis, medial forebrain bundle, inferior thalamic peduncle, stria terminalis, stria medullaris, mammillary peduncle, and dorsal longitudinal fasiculus. Dense fiber plexuses were present throughout the hypothalamus; however, NPY‐IR was conspicuously absent from the suprachiasmatic nucleus. Immunoreactive perikarya were located in the supraoptic, dorsomedial, ventromedial, and arcuate nuclei, in the external division of the ventral lateral geniculate nucleus, and in the pineal gland. Localized changes in density and/or distribution of NPY‐IR were correlated with changes in physiological state.