Premium
Projections from the anterior ventral cochlear nucleus to the central nucleus of the inferior colliculus in young and aging C57BL/6 mice
Author(s) -
Willott James F.,
Pankow David,
Hunter Kelly Paris,
Kordyban Mary
Publication year - 1985
Publication title -
journal of comparative neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.855
H-Index - 209
eISSN - 1096-9861
pISSN - 0021-9967
DOI - 10.1002/cne.902370410
Subject(s) - inferior colliculus , inferior colliculi , biology , superior colliculus , anatomy , neuroscience , wheat germ agglutinin , cochlear nucleus , nucleus , presbycusis , hearing loss , audiology , medicine , biochemistry , lectin
Projections from the anterior ventral cochlear nucleus (AVCN) to the central nucleus of the inferior colliculus (ICC) were studied in young and aging C57BL/6 mice. The latter animals demonstrate progressive loss of hearing. Wheat germ agglutinin‐horseradish peroxidase (WGA‐HRP) was injected into the inferior colliculus and retrograde transport to the AVCN was evaluated. No age‐related differences were found in the area of AVCN sections, quality or labelling, number of labelled neurons adjusted for injection size, or topographic organization of projections. Thus, despite progressing loss of auditory sensitivity, chronic profound hearing loss (oldest animals), and aging, projections from AVCN to ICC remain stable.