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The distribution of nine peptides in rat spinal cord with special emphasis on the substantia gelatinosa and on the area around the central canal (lamina X )
Author(s) -
Gibson Sally J.,
Polak Julia M.,
Bloom Stephen R.,
Wall Patrick D.
Publication year - 1981
Publication title -
journal of comparative neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.855
H-Index - 209
eISSN - 1096-9861
pISSN - 0021-9967
DOI - 10.1002/cne.902010106
Subject(s) - neurotensin , cholecystokinin , enkephalin , biology , neurophysins , vasoactive intestinal peptide , medicine , endocrinology , spinal cord , neuropeptide , substance p , thyrotropin releasing hormone , hormone , peptide , biochemistry , neuroscience , opioid , receptor
The comparative distribution of nine peptides was examined in the L4 segment of the rat cord using the peroxidase antiperoxidase technique. The peptides examined were substance P, neurotensin, cholecystokinin, methionine‐enkephalin, oxytocin, neurophysin, adrenocorticotrophin, thyrotropin releasing hormone, and vasoactive intestinal polypeptide. No transport blocking agents were used and in spite of this cell bodies containing substance P, neurotensin, cholecystokinin, and methionine‐enkephalin were observed. All peptides except for thyrotropin releasing hormone were observed in fibers in laminae I and II. All peptides were present in the area around the central canal, lamina X . Each peptide had its own characteristic distribution within fibers in the gray and white matter.