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A study of Golgi preparations from the human lateral geniculate nucleus
Author(s) -
Hickey T. L.,
Guillery R. W.
Publication year - 1981
Publication title -
journal of comparative neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.855
H-Index - 209
eISSN - 1096-9861
pISSN - 0021-9967
DOI - 10.1002/cne.902000407
Subject(s) - parvocellular cell , lateral geniculate nucleus , biology , golgi apparatus , nucleus , axon , neuroscience , dendrite (mathematics) , geniculate , anatomy , microbiology and biotechnology , retina , geometry , mathematics , endoplasmic reticulum
Abstract The Golgi method was used to study nerve cells and their processes in the human lateral geniculate nucleus. Only a few axons were successfully impregnated. These enter the nucleus from the optic radiations and were tentatively indentified as corticogeniculate axons. In one brain from a 2‐week‐old infant these axons showed unusually dense terminal arbors, suggesting that significant developmental changes occur in this fiber system postnatally. Neurons in the magnocellular layers show a great variety of dendritic patterns, and are not readily grouped into well‐defined morphological classes. At one extreme are cells with a restricted dendritic arbor, having dendrites that run a sinuous course close to the perikaryon. At the other extreme, cells have a more extended dendritic arbor; their dendrites are long, relatively straight in some cells, markedly tortuous in others. There is a continuous range of intermediate cell types between the “restricted” and the “extended” cells. Many magnocellular dendrites cross freely into adjacent layers; whereas the short dendrites of restricted cells rarely cross from one layer to another, the dendrites of extended cells may either be confined to a single layer (intralaminar) or may have a translaminar distribution across two or even three layers. Small cells, with dendrites entirely confined to an interlaminar region, have been seen in the magnocellular division of the nucleus on either side of layer 2. Parvocellular elements also show a wide range of dendritic patterns, but the extreme forms of restricted and extended cells are not seen. Parvocellular dendrites commonly are oriented perpendicular to the layers and generally show an intralaminar distribution; translaminar dendrites are extremely rare. A minority of parvocellular neurons have most of their dendrites confined to an interlaminar zone. These “interlaminar” cells have large perikarya close to or in the interlaminar zones, and show a predominant dendritic orientation parallel to the layers. A few parvocellular elements with complex axoniform dendrites were seen, and these dendrites, too, tend to run parallel rather than perpendicular to the layers.