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The nervus terminalis of the guinea pig: A new luteinizing hormone‐releasing hormone (LHRH) neuronal system
Author(s) -
SchwanzelFukuda M.,
Silverman A. J.
Publication year - 1980
Publication title -
journal of comparative neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.855
H-Index - 209
eISSN - 1096-9861
pISSN - 0021-9967
DOI - 10.1002/cne.901910205
Subject(s) - biology , forebrain , anatomy , terminal nerve , guinea pig , olfactory nerve , central nervous system , hormone , endocrinology , olfactory bulb
Immunoreactive LHRH‐like material has been found in the cells and fibers of the nervus terminalis in fetal and adult guinea pig brains. LHRH‐containing neurons and axons are seen in the nasal mucosa intermingled with fibers of the olfactory nerves, in ganglia along the ventromedial surfaces of the olfactory bulbs and forebrain, and in clusters surrounding perforating branches of the anterior cerebral artery in the regions of the septal nuclei and olfactory tubercle. Nonreactive neurons are found adjacent to the LHRH‐positive cells in all of the ganglia. LHRH‐immunoreactive cells and axons of the nervus terminalis are in intimate contact with cerebral blood vessels and the cerebrospinal fluid along the intracranial course of this nerve, deep to the meninges. The possible involvement of these structures in the neural mechanisms of sexual behavior and the neurohormonal regulation of reproductive function are discussed.