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DNA constancy in neurons of the human cerebellum and spinal cord as revealed by Feulgen cytophotometry and cytofluorometry
Author(s) -
Fujita Setsuya
Publication year - 1974
Publication title -
journal of comparative neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.855
H-Index - 209
eISSN - 1096-9861
pISSN - 0021-9967
DOI - 10.1002/cne.901550205
Subject(s) - feulgen stain , neuroblast , biology , cerebellum , spinal cord , dna , anatomy , pathology , neuroscience , genetics , neurogenesis , medicine
Neuroblasts and neurons of the human cerebellum and spinal cord from the eighth fetal week to 68 years of age were prepared as smears and the DNA content of individual cells was measured by Feulgen cytophotometry and microfluorometry. DNA constancy of large and small neurons as well as neuroblasts was confirmed by the two methods. These findings accord with autoradiographic observation that neuroblasts, once differentiated from matrix cells, do not synthesize DNA.