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The effects of monocular lid suture upon the development of the visual cortex in squirrels ( Sciureus carolinensis )
Author(s) -
Guillery R. W.,
Kaas J. H.
Publication year - 1974
Publication title -
journal of comparative neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.855
H-Index - 209
eISSN - 1096-9861
pISSN - 0021-9967
DOI - 10.1002/cne.901540406
Subject(s) - nissl body , biology , lateral geniculate nucleus , visual cortex , anatomy , cortex (anatomy) , monocular , orientation column , striate cortex , geniculate , neuroscience , nucleus , staining , optics , genetics , physics
Three infant squirrels had the lids of one eye sutured prior to eye opening. The animals were killed when they were adults and the cells in the visual cortex were studied after Nissl staining. On the side contralateral to the suture, the cortical nerve cells were more closely packed than on the side of the suture. This asymmetry was clearly evident in cortical layers II–VI, and it was as marked in the regions of cortex receiving from the monocular crescent of the visual field as it was in the binocular segments. Thus, these cortical changes cannot be dependent upon the geniculate cell changes, since the latter occur in the binocular but not the monocular segments of the nucleus.